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Moreover, SOX2-positive melanoma cells tend to be more spindle-shaped and have more peripheral nestin pattern, which may represent a motile, more mesenchymal phenotype [26]

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AOD 9604 is a synthetic fragment of human growth hormone, specifically amino acids 176 through 191 of the hGH sequence, with a single modification at the N-terminus for stability

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Cell migration was monitored in real time using a cultured cell monitoring system (CCM-1.4XYZ/CO2, Astec Co.) and wound closure area was measured using CCM software

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32 This is due to metabolic reprogramming in the BM niche, which shifts from oxidative phosphorylation to aerobic glycolysis reducing ATP and simultaneously increasing NAD +

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