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Inibisce inoltre la produzione di citochine pro-infiammatorie (TNF-, IL-6, TGF- in eccesso) stimolando al contempo le citochine antinfiammatorie (IL-10)

The four amino acid substitutions confer resistance to DPP-IV, the primary enzyme responsible for cleaving the native GHRH N-terminus, but the peptide remains susceptible to other circulating proteases

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It has also been linked to reduced wrinkle depth and thicker skin

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