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Wiesenberger, G

Center for Drug Evaluation and Research (CDER) and Center for Biologics Evaluation and Research (CBER) U.S

For the intact cell experiments, the cells treated with (+)-CLA (20 M) for 24 h were heated as above described followed by lysis using three cycles of freeze-thawing with liquid nitrogen

However, long-term use at high doses can lead to refractory symptoms and drug-induced side effects in some patients [104]

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Following adequate growth, a suspension of cells (density of 5 10 3 cells/well) was inoculated onto 96-well plates and cultured in full medium for 24 h
