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GLUT-1: an effective target to deliver brain-derived neurotrophic factor gene across the blood brain barrier

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Methods 25:402408 Pinheiro AC, Bourbon AI, Cerqueira MA et al (2015) Chitosan/fucoidan multilayer nanocapsules as a vehicle for controlled release of bioactive compounds

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These observations highlight the need for large-scale, multicenter, randomized, placebo-controlled trials to ascertain whether targeted modulation of specific probiotic strains or other gut microbes associated with a lean phenotype can effectively counteract obesity and improve insulin sensitivity

Isolated GHD is caused by mutations in GH1, BTK, and RNPC3 while GHD seen as part of multiple pituitary hormone deficiency is known to be caused by mutations in a wide variety of genes