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SLC36A4 (hPAT4) is a high affinity amino acid transporter when expressed in Xenopus laevis oocytes
The subsequent increase in metabolic rate leads to a reduction in white adipose tissue and has been shown to produce significant weight loss in preclinical studies without affecting appetite
The sequence corresponds to amino acids 177191 of native human growth hormone with an N-terminal tyrosine added to improve in vivo stability
Most ATMs in young adipose tissue are M2
