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Benefit: Neuroprotection Focus Area: Brain & Nerves Mechanism of Action: Studied for its ability to reduce inflammation in the CNS and aid nerve regeneration

It is particularly prevalent in patients taking metformin (which blocks B12 absorption), vegetarians and vegans, patients with atrophic gastritis or prior gastric surgery, and older adults with reduced intrinsic factor production

Injecting fasted with no food for roughly two hours before and staying fasted for ~3060 minutes after lets the pituitary pulse without that interference

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Pernicious anemia, however, can cause major health issues like nerve damage and heart failure if left untreated

New Zealand Medicines and Medical Devices Safety Authority