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Mitochondrial dysfunction leads to the decrease of NAD + level, resulting in lysosomal acidification and impaired autophagy, and induces ferroptosis, involving the accumulation of iron in lysosomes and lipid peroxidation

In addition to medications that cause false alterations in thyroid lab results, there are also medications that have actual drug interactions with thyroid hormones, and the altered labs are a real reflection of how the addition of a new drug impacts the activity of thyroid hormones in the body