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Bottom line: Higher NAD+ = better energy, sharper cognition, and cellular longevity

Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts

doi: 10.1016/j.msec.2020.111660

As such, the AMYR agonists (combined with other incretin class members) could represent the elusive drug candidate to address the multi-hormonal dysregulations of diabetes subtypes and qualify as a precision medicine approach that surpasses the long overdue division into T1DM and T2DM

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The right option depends on the patients symptoms, goals, safety needs, and provider recommendation