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33 Last but not least, NETs can cause mitochondrial damage, resulting in the release of mtDNA, which can activate the NLRP3 inflammasome in the diabetic wound

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The inhibition of ATG5, a mediator of autophagy in hypoxic cancer, can induce cisplatin sensitivity in previously resistant cells (188), supporting the contribution of hypoxia-induced autophagy to the development of anticancer drug resistance

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