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MECHANISM CATEGORIES SAFETY Side effects Generally well-tolerated in trials at the doses tested Injection-site reactions Known interactions Not characterized in Phase 3 Contraindications Pregnancy/lactation (unstudied) REGULATORY STATUS FDA Not FDA-approved as a drug

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Guide for the Care and Use of Laboratory Animals , 8th ed, 220 (National Academies Press, 2011)

Yes, lipo B12 injections are considered safe when recommended under medical guidance

Clinical trials conducted in the early 2000s showed modest results, and the compound failed to demonstrate sufficient efficacy to support regulatory approval as a weight-loss medicine

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