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Nrf2 also regulates the expression of genes that control inflammatory and immune system responses (Kasprzak et al., 2020)

Proc Biochem 42:454458

Sirts have also been linked to longevity in model organisms and protective effects in cardiac and neuronal models.13 A recently identified NAD+ hydrolase, Sterile Alpha and Toll/Interleukin-1 Receptor motif-containing 1 (SARM1), is implicated in the aging and regeneration of neurons (21,22)

doi: 10.1016/j.ifset.2024.103697 56 KhoddamiAWilkesMARobertsTH

Holladay, and K

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