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Indirect antioxidants may or may not be redox active and exert their biological effects through induction of cytoprotective genes that recycle and/or regenerate direct antioxidants

Frequent repeated injections are required to prevent a rebound effect with no clearly defined endpoint.128 Campochiaro et al.129 presented preliminary results of a randomized study in the treatment of BRVO with intravitreal injection of ranibizumab at the 2007 Annual Meeting of Association on Research and Vision in Ophthalmology (ARVO)

Hdac expression and activity is upregulated in diseased lupus-prone mice

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Lipid peroxidation of unsaturated fatty acids produces lipid peroxyl radicals (ROO), which diffuse easily in biological systems