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Especially, FBD3 showed nearly identical potency and efficiency as fentanyl in either cAMP inhibition or Gi recruitment assays but had very limited -arrestin recruitment activity (Figure 6b-c)

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Skin retention is measured by the same analytical techniques as used for skin permeation assessment, e.g., HPLC or spectrophotometry

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This guide to Selank is part of our ongoing series on therapeutic peptides, an endeavor into which weve put more than 1,000 cumulative research hours

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doi: 10.1093/brain/awp029

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