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Description
AIT involves regular exposure to increasing doses of the allergenin this case, shellfish proteinsto induce desensitization and tolerance
However, excessive exercise can lead to excessive accumulation of ROS, surpassing the bodys antioxidant defense capacity, thus inducing oxidative damage

Among the more than 20 identified aflatoxins, AFB 1 is the most toxic and has been classified as Group I carcinogen by the International Agency for Research on Cancer (IARC), due to its hepatoxicity, nephrotoxicity, immunotoxicity, teratogenicity, and mutagenicity [3,4,5,6]
10.1093/nar/gkz430 257 TaylorH

Aside from technical challenges, SCT also faces issues with lack of standardized protocols and quality control systems
Organoids, due to their capacity to replicate the original tumor characteristics and immune microenvironment, are recognized as powerful tools for studying cancer immunotherapy [197]