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Description
The mitochondrial toxin 3-nitropropionic acid (3NP) is commonly used to create HD animal models

Levi-Montalcini and Aloe (1997)

It exclusively cleaves a single C-terminal residue from Ang-II generating Ang-(1-7), thus counterbalances the accumulation of Ang-II formed by the action of ACE

Therefore, future studies should focus on the precise regulation of the ghrelin-ENS pathway by specific functional microbiota, providing a basis for developing DGE treatment strategies that balance motility improvement and glycemic stability

M.CooperD

Gut microbiota dysbiosis in PD patients may increase intestinal permeability, exposing the enteric plexus to various toxins
