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The first protein shown to be modified by succination was glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
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GLP-1 exerts antidiabetogenic properties in subjects with type 2 diabetes by stimulating insulin secretion, increasing -cell mass, inhibiting glucagon secretion, delaying gastric emptying, and inducing satiety, thus slowing the entry of sugar into the blood
