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Abeta-Cu 2+ complexes are redox-active, and therefore they can release reactive oxygen (Smith et al., 2006)

Through conducting hesperitin investigations, it was shown that mitochondrial apoptosis, neuroinflammatory, and transcription factors, which are controlled to reduce oxidative stress, are some of the triggering factors to induce neurodegeneration

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doi: 10.1038/s41586-018-0466-7

When combined with GLP-1's appetite suppressive effects, the result is weight loss achieved through both reduced caloric intake and improved energy expenditurea more sustainable metabolic profile than appetite suppression alone