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L., Bemben, D

Gene expression modulation: Experimental studies suggest the peptide may influence gene regulatory mechanisms involved in metabolic control, oxidative stress response, and cellular repair processes

demonstrated that anti-angiogenic therapy with anti-VEGFR2 enhances the efficacy of anti-PD-L1 immunotherapy in pancreatic neuroendocrine tumor (RT2-PNET), mammary carcinoma (MMTV-PyMT), and glioblastoma (NFpp10-GBM) models 88

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Strategies for targeting senescent cells in human disease