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Iron regulatory proteins and their role in controlling iron metabolism

Author contributions MH: Conceptualization, Writing original draft, Writing review & editing

RPE is particularly susceptible to oxidative stress due to its role in phagocytosis of photoreceptor outer segments 2

A revision is warranted as more evidence emerge relating genotype with phenotype, genetic variant classes and enzyme activity, and discovery of novel mutations

This opens up a unique and promising new field of research