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In addition to low serum levels of carnitine these patients have decreased intracellular carnitine accumulation

In a diet-induced obese mouse model, amkinone at 10 mg/kg/day dose showed improvement in glucose tolerance and insulin sensitivity concomitant with the reduction in adiposity and body weight without affecting food consumption

The importance and potential efficacy of carnitine in the treatment of lung diseases is gradually being recognized [306, 307]
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