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Kwok WC, Tam TCC, Lam DCL, Ip MSM, Ho JCM
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This degeneration results in a loss of the associated rods and cones
Structural optimization of DEL7 with restrictions on net charge led to discovery of analogs with improved antiviral potency for SARS-CoV-2 Aiming to optimize the DEL7 structure into a potent antiviral inhibitor in cellular context, we prioritized synthesizing DEL7 analogs with less net charge than 14
