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Description
625 NRD.E1 is a novel non-opioid therapeutic that is being developed for the treatment of PDPN
In this cancer, the failure of imatinib mainly depends on mutations of the tyrosine-protein kinase KIT and the platelet-derived growth factor receptor (PDGFR)
Treatment usually consists of dietary supplements, avoidance of fasting and prolonged exercise, and treatment of complications, such as myoglobinuria, hypoglycemia, and hepatic dysfunction
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doi: 10.1542/peds.2014-0329
