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Kovalenko Systemic Hypertension.2022

Implantation of a foreign body causes an inflammatory response followed by the release of TGF-1 and activation of myofibroblasts, which deposit large amounts of collagen and cause contraction of the tissues, leading to implant deformities and pain ( The list of conditions where fibroblasts actively contribute to pathogenesis seems endless

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Ilkaeva O, Kinch LN, Paulssen RH, Ross EM

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