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Comparing the Subjective, Psychomotor and Physiological Effects of Intravenous Nalbuphine and Morphine in Healthy Volunteers

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Moreover, despite the relief opioid drugs can provide for acute clinical and experimental pain (Wanigasekera et al., 2012), psychosocial stress (Bershad et al., 2015, 2018), certain depressive symptoms (Pecia et al., 2018), and feelings of breathlessness (Hayen et al., 2017), opioid blockade does not consistently increase the aversiveness of experimental pain (Anderson et al., 2002

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[DOI] [PMC free article] [PubMed] [Google Scholar] 302.Rafiq S, Yeku OO, Jackson HJ, Purdon TJ, van Leeuwen DG, Drakes DJ, et al

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Mid-stage symptoms (as the condition progresses) Daytime numbness or tingling that doesn't go away with hand shaking

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