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Flexural sites are defined as sites with cutaneous folds, including axilla, mammary folds, popliteal and antecubital fossae, umbilicus, pubis, scrotum, and perianal skin, but also folds on the neck and abdomen

Apply drops directly to affected areas after cleansing

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When the analyte is added to the matrix, the thermally induced proton transfer model predicts that if the proton-transfer efficiency between the matrix and the analyte is greater than that between matrix molecules, the total number of ions can increase significantly

Any minor surgical procedures might lead to invasiveness which was observed in our case after an incisional biopsy