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3 To restore the entire nigrostriatal pathway with appropriate inputs and outputs remains a considerable challenge, as implantation of only dissociated cells cannot restore the key anatomic features of damaged pathwaysnotably long axon tracts projecting to proper anatomical structures

These results suggest that the reduction in infectivity cannot be attributed solely to decreased viral production, but instead may reflect compound-specific effects on infectivity of the released viral particles

157,158,159,160,161,162 The effect of PARPs to stimulate chromatin decompaction might be exerted via the steric hindrance of PAR chain, the negative charge of DNA and PAR, or the displacement of core histones

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M., Marchionno, L., Gambi, D., Pirchio, M., Del Rosso, G., and Albertazzi, A

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