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(8) Guerini et al in their review highlight this issue, and show that NAC can be very helpful in disrupting biofilms, along with its mucolytic and antioxidant role, especially Pseudomonas aeruginosa

Iranian Journal of Child Neurology 15 (3): 3546

A higher antioxidant dose does not guarantee a greater health benefit

But the skepticism is actually very reasonable

A cutoff value of 10.2 nmol/mg for GSH was identified, and the area under the ROC curve was 0.913, with a sensitivity of 90.2% and a specificity of 81.8%, demonstrating significant predictive capability in differentiating between the resistant group and sensitive group

May be repeated once or twice weekly, as indicated by condition and response