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1 In either model portal venous and arterial blood flow centripetally, that is, toward the central vein, whereas bile flows centrifugally, that is, away from the central vein
doi: 10.1016/j.dld.2014.11.003 9 XueJSharmaVHabtezionA

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About 10% of people with GIST have a form of the disease known as SDH-deficient GIST

Role of somatostatin in the regulation of central and peripheral factors of satiety and obesity
And now it's sort of a back and forth within the field