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JCR Pharmaceuticals and Denali Therapeutics have potential enzyme replacement therapies for Sanfilippo type A and/or B in their pipeline that have been specially engineered to cross the BBB

doi: 10.2337/dc07-0589

Santos, J

[2] Jung, S

This stack supports: Youthful skin and collagen production Energy, focus, and metabolism Immune resilience and detox support Healthy aging from the cellular level Aging is inevitable but how we age is optional

Given that PIP 2 has pleiotropic functions in cells including receptor endocytosis (see below), other potential mechanisms for PIP 2 in LRP6 phosphorylation remain to be explored