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To draw RNA structures containing sequences predicted to form G4 structures, the ViennaRNA constraint option was employed, forcing the putative G4 tract to remain unpaired during secondary-structure prediction 59

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Although the current therapeutic practices have significant variability in routes and dosage regimens, we concluded that management of IGS predominantly centers on lifelong Vitamin B12 supplementation, which is sufficient for preventing hematological and neurological abnormalities associated with this disorder

Interestingly, comparing to experimentally used iodine in excess, herbs with excess iodine damage rat thyroid follicular cells less, which may be related to high antioxidant capacity of these herbs [192]

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PubMed Central, Malir, Frantisek, et al