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It is also evident that many of the antioxidant enzymes are induced by GSH depletion at the transcriptional level which involves the binding of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) transcription factor to the antioxidant response element (ARE) in the promoter region of the genes encoding GCL and glutathione S -transferases [16]

Pharmacogenetic interactions in G6PD deficiency and development of an in vitro test to predict a drugs hemolytic potential

Nguyen TP, Nguyen TH, Tran TT

Mitochondrial targeted antioxidants, mitoquinone and SKQ1, not vitamin C, mitigate doxorubicin-induced damage in H9c2 myoblast: pretreatment vs

Free Report Caxaria S, Sikandar S, et al
Moreover, under the regulation of enzymes, GSSG and GSH in organisms are usually in a steady dynamic equilibrium
