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3E), indicating LL-341070 does not protect oligodendrocytes from death as other thyromimetics have been shown to do in other models 57
10.1016/S0306-4530(97)00076-0 Psychoneuroendocrinology
[DOI] [PMC free article] [PubMed] [Google Scholar] 37.Orlandi, I., Alberghina, L
& McDermott, M
Unlike NAD+ precursors that work downstream, 5-Amino-1MQ acts upstream by blocking NNMTs consumption of S-adenosyl methionine (SAM), resulting in elevated intracellular NAD+ and SAM levels without requiring direct nucleotide supplementation
