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In addition, Rb1 can prevent Tau protein phosphorylation and thus aluminum-induced neurotoxicity by regulating the levels of p-GSK3 and PP2A, further exerting neuroprotective effects (Zhao et al., 2013)
166 Moreover, epigenetic modifications (primarily aberrant histone modifications) have been seen in Huntingtons disease
TAZ: transcriptional coactivator with PDZ-binding motif
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In a sepsis model, DEX can reduce ferroptosis and protect important organ damage by enhancing glutathione peroxidase 4 (GPX4) expression (Wang et al., 2020a)
