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Indeed, local injection of oxalate into the footpad of mice induces spontaneous nocifensive behavior as well as mechanical allodynia, albeit the dose required to observe this effect is considerably higher than the dose of oxaliplatin required to induce neuropathic pain (Deuis et al., 2013)

The medication is typically injected once weekly on the same day

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CIPN happens when the nerves outside of the brain and spinal cord, called the peripheral nerves, are damaged by chemotherapy drugs

Exercise Recovery: L-carnitine supplementation may help reduce muscle damage and soreness after exercise, promote recovery, and support muscle repair and growth

Prior to the study, animals were acclimated for one week to minimize stress