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[45] also reported that melatonin alleviated 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced hypertension by decreasing renal oxidative stress and vascular reactivity
[DOI] [PubMed] [Google Scholar] 40.Stamler J, Wentworth D, Neaton JD
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The accumulation of propionate and the blockade of its metabolism have synergistically detrimental effects on various organs, with neurological dysfunctions being one of the most common complications in PA patients ( In this minireview, we summarize the current understanding of propionate sources, metabolism, and its pathological roles in neurological dysfunctions when its metabolism is impaired in PA

Hoffmann-La Roche, and Merck & Co

Lancet 2021;398:26276
