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Description
PD-linked mutations may interfere with any of these pathways, leading, e.g., to decreased lysosomal degradation of -synuclein aggregates or increased aggregation of -synuclein due to oxidative damage downstream of ROS release from defective mitochondria

These compounds may help by reducing gastric acid secretion and enhancing mucosal defense mechanisms

The advantages of this molecule include its small size which ensures good NMJ penetration, ability to concomitantly administer IVIg therapy since this is not an antibody and the potential for self-administration (given the once daily subcutaneous route of delivery) [85]

doi: 10.1111/pedi.12870 176 MarinoKRLundbergRLJasrotiaAMarandaLSThompsonMJBartonBAet al

Mild bruising at injection sites occurs occasionally, especially in individuals new to subcutaneous injection

Ratios were log transformed to create a normal distribution for all ratio data within each run for all samples