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Human serum albumin (HSA) and ceruloplasmin (CP) maintain the dynamic equilibrium of copper in the serum via distinct binding properties: CP stabilizes and stores most of the copper, while HSA is the primary carrier for exchangeable copper, aiding in copper transport and distribution (24)

Injectable forms (investigational) carry potential risks such as infection or inflammation, as suggested by case reports [10]

Moreover, the evidence of long-term outcomes requires further strengthening

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Adult growth hormone deficiency treatment with a combination of growth hormone and insulin-like growthfactor-1 resulting in elevated sustainable insulin-like growthfactor-1 and insulin-like growth factor binding protein 3 plasma levels: a case report