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Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites

The slow exchange regime on the NMR timescale suggested a tight binding, which was confirmed by measuring the binding affinity of BRD4 ET to ASXL1 EBM by ITC

The aim is to offer valuable insights to support the development of novel therapeutic approaches and enhance clinical management of this challenging side effect

Abstract Inability to achieve therapeutic concentrations of a medication in the brain due to the blood brain barrier (BBB) is the major cause of treatment failure for most brain diseases

Commonly these symptoms are categorized as psychosomatic or medically unexplained symptoms (MUS) [43]

doi: 10.1038/s41398-022-02149-9