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The top 10 proteins based on degree and BC score for both drugs are listed in Supplementary Tables S2-S5 (Supplementary File 2) while the full ranking of the proteins is listed in Supplementary File 1

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Materials and methods Chemicals and reagents All chemicals and reagents utilised in this study were of analytical and purified grade, sourced from Sigma-Aldrich Ltd, UK, and British Drug Houses (BDH) Ltd, UK

Conclusion# Amycretin and CagriSema illustrate two philosophies for combining GLP-1 and amylin receptor activation

Las venas varicosas, las vnulas y telangiectasias, no deben ser eliminadas, no deben ser destrudas, no deben ser ligadas, no deben ser quemadas deben ser simplemente curadas