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While glutathione and melatonin are recognized as antioxidative agents [137], ASA has been shown to increase intracellular HIF1 expression, simulating hypoxic conditions and providing protection against oxidative damage [138]

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All activity evaluations confirmed that disulfide bonds were important structures for bioactivities (Dai et al

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Ishiguro K, Sato K, Takamatsu M, Park J, Uchida T, Imahori K

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