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We also summarize newly proposed mechanisms associated with hepatoprotection and tumor suppression, such as attenuation of hepatocellular stress through inhibition of the NEDD9/FAK/AKT cascade and a potential role in cell-cycle regulation via the HDAC/p21 axisalthough the latter remains to be validated in MASLD-specific models

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ruthenicum alleviated the nonalcoholic fatty liver disease by enhancing the AMPK signaling pathway (Lin et al., 2015), suggesting the significance of the AMPK signaling pathway in response to the treatment of mice with EIF by the fruit extracts of L

In this review, we selected articles that include the protective effects of CoQ10 against the toxicity of various chemical and natural compounds including pharmaceuticals, metals, pesticides, etc

IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts