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Yes, B12 shots are generally safe for most people

Thank you for the convenience of doing home injections

SCFA metabolites, such as acetate, propionate, and butyrate, can act on fatty acid receptors in epithelial, enteroendocrine, and neuronal cells, and they could affect the central nervous system in experimental model organisms (53, 54)

Injectable folic acid preparations containing benzyl alcohol should be avoided in neonates because benzyl alcohol has been associated with gasping syndrome, a potentially fatal condition characterized by metabolic acidosis and CNS, respiratory, circulatory, and renal dysfunction

(April 2014)

N.et al (2021)