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NAD+ is a coenzyme found in every cell that helps convert nutrients into energy

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It is thought that the secondary pathway by which AOD9604 causes fat loss, the pathway that is independent of beta-3-adrenergic receptor activation, may play a role in improving metabolic metrics even while it boosts fat loss- AOD9604 exhibits minimal side effects, high oral and excellent subcutaneous bioavailability in mice

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Preclinical studies in obese mouse models showed that NNMT inhibition with 5-Amino-1MQ reduced adipocyte size and body weight without changes to food intake, suggesting effects on energy expenditure rather than appetite

Weight loss reduces the production of these cytokines, lowering overall inflammation levels