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Human studies consistently report that doses up to 6 g are well tolerated, with no adverse effects noted even in older adults
Overall, whilst these findings imply that increased production of ROS is associated with C9orf72-ALS, it is unclear whether loss of C9orf72 or expression of hexanucleotide repeat expansions disturbs redox homeostasis
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doi: 10.3322/caac.21338 72 ImaizumiMUsaTTominagaTNeriishiKAkahoshiMNakashimaEet al
When paracetamol is taken in large quantities, a minor metabolite called N -acetyl- p -benzoquinone imine (NAPQI) accumulates within the body
