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M.BorziA

While the origins of the observed differences between mice and humans with respect to the l-carnitineBBTMATMAO pathway are not clear, the fact that the second reaction in the conversion of l-carnitine into TMA (i.e., BBTMA) showed marked induction with dietary exposure in subjects likely plays a major role in the observed differences

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One unit (U) of enzyme activity was defined as the amount of enzyme which produced 1 mol FAME in 1 min under the assay conditions

On the other hand, Lp(a) is characterized by the presence of a specifically hydrophilic and highly glycosylated apolipoprotein (a) [apo(a)] that is covalently attached to the apo-B100 molecule by means of a single disulphide bond [22,23,24]