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In humans, impaired stomach lining stems from gastric surgery, chronic inflammation or pernicious anemia a medical condition characterized by fatigue and a long list of other symptoms

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The endogenous antioxidants in melanocytes comprise enzymes, such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR) and Trx reductase (TrxR)

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In addition, elevated GSH is related to a loss of positive affect, providing further evidence for a link between GSH alterations and anhedonia in affective disorders
