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215 Astragalus inhibits ferroptosis in synovial cells and exerts a protective effect through activation of the SLC7A11/GPX4 axis

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This direct inhibition means faster visible results, but also higher risk of irritation

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To validate these findings in vivo, we assessed lipolysis in AAV-shRNA-mediated Gpr146 knockdown mice following stimulation with CL316,243, a 3-adrenergic receptor agonist

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This allows further exploration of the therapeutic effect of the Scrophularia Radix-Fritillaria prescription

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