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McCarley et al

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It is hypothesized that decreased hypocretin production in SAH and DID patients is associated with altered hypocretin signaling in response to ischemia [144]
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AMPK not only stimulates PGC-1 transcription, but also activates it by phosphorylating threonine-177 and serine-538, enhancing PGC-1 co-transcriptional activity and promoting mitochondrial biogenesis [34]

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