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Protein, electrolytes, and sleep are the first variables to assess

The consistency across dose groups is telling

Although a possible neurotransmitter role was claimed, i.e., for prostaglandins [144,145,146,147] and somatostatin [148,149,150], this was not combined with the cytoprotective effect and possible pleiotropic effect (organoprotection)

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Similarly, iron overload is implicated in promoting fibrosis [99]