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Preclinical and clinical trials should be designed accordingly, with a focus on conditions where antioxidant therapy is more likely to yield therapeutic benefit

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In addition, retrospective reevaluation of patients with a diagnosis of Reyes syndrome who survived has revealed that many, if not most, had an underlying inborn error of metabolism (IEM)

The status of glutathione defense system was determined by measuring the level of reduced glutathione, as well as the activity of the enzymes: superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione-S-transferase (GST) in the erythrocytes

Molecules, 17 (2), 20302048

Weeks 13-16: 7 to 10 mg daily